Our Story
Again and again, they supported scientists, companies and organizations pursuing remarkable technologies. Yet the same problem persisted. Promising science advanced, but human application remained somewhere in the future.
Eventually, Kenneth and Helga decided to stop passing responsibility for translation to others. They would manage the process themselves.
They teamed with Patrick Sewell, MD, CEO of Triple Helix Science, on the scientific front to create the Rejuvenation Cocktail. From the beginning, it was designed with older people particularly in mind—a population with the most immediate need for restored muscle, cognition, metabolic resilience and function, yet one routinely neglected in the development of emerging therapies.
At the same time, Kenneth and Helga moved forward on the organizational front, creating the KHL Foundation in Panama. KHL was not created simply to deliver one therapy. It was built as a framework for repeatedly moving promising rejuvenation technologies from scientific possibility into human application.
Within months, the two efforts came together. The Rejuvenation Cocktail became the first major demonstration of the model, and Kenneth and Helga became its first recipients. Further KHL initiatives are already beginning to follow.
Nobody handed them this responsibility. People in their ninth decade are more often expected to surrender responsibility than assume it. Kenneth and Helga did the opposite. They see older people not as society’s spent generation, but as an enormous reservoir of accumulated knowledge, talent and experience worth restoring and preserving.
We created the therapy, built the vehicle and established a process designed to do it again.
How we work
Develop. Apply. Monitor. Adapt.
Creating the therapy and the organization to deliver it confirmed something our earlier experience had already taught us: better science alone was not enough. We needed a better process for moving science into humans.
Creating the therapy and the organization to deliver it confirmed something our earlier experience had already taught us: better science alone was not enough. We needed a better process for moving science into humans.
So we developed one.
D
Develop
Find promising science and turn it into something that can actually be delivered. Bring together scientists, entrepreneurs, manufacturers, physicians and the resources needed to move from an idea to a usable therapy.
A
Apply
Get it into humans. At some point, laboratory promise has to become human experience. That is where we begin to discover what a therapy actually does.
M
Monitor
Measure what happens. Look for what we expected—and what we did not expect. Biomarkers matter, but so do strength, cognition, mobility, resilience and the everyday experience of the people receiving the therapy.
A
Adapt
Learn from the experience and make the next application better. Improve the therapy, the delivery, the measurements and the process itself. Then do it again.
Develop → Apply → Monitor → Adapt.
We call it DAMA.
It replaces waiting for the perfect answer with a continuing cycle of application, measurement, learning and improvement.
Meet the Founders
Kenneth Scott and Helga Sands are not observers of rejuvenation. They are participants.
Now in their ninth decade, they bring a lifetime of experience in science, business, finance, investment and entrepreneurship to KHL—and personally participate in the rejuvenation therapies they help bring to humans.
Books, research and publications
KHL's ideas do not stop at the clinic.
We write about what we have learned, challenge conventional thinking about aging, develop the scientific and policy arguments behind what we do, and put those ideas into books and the scientific literature.
AVAILABLE NOW
Born to Live
Reflections from My 9th Decade
Written from the perspective of more than eight decades of living, working, experimenting and refusing to accept conventional expectations of age, Born to Live explores what it means not simply to survive into old age, but to remain independent, engaged and purposeful.
The book introduced ideas that continue to shape KHL’s thinking, including the distinction between simply living longer and retaining the function and independence that make those years productive and enjoyable.
COMING SOON
Forget Aging, Start Rejuvenating.
The next book takes the argument considerably further.
Forget Aging! Start Rejuvenating. starts from a different premise: aging is no longer something we should simply describe, manage or accept. Emerging science increasingly gives us the opportunity to restore lost function and rejuvenate the living generation.
Drawing on Kenneth and Helga’s personal experience, their work with emerging therapies and the development of KHL, the book examines rejuvenation function by function—from muscle, hearing, vision, teeth and skin to the brain and other organs—and asks a practical question:
What can we do now?
At its heart is the KHL approach: Develop → Apply → Monitor → Adapt.
Research Submitted for publication to SEMAL
Integrated Longevity Triad (ILT)
The Integrated Longevity Triad is the technical specification underlying the KHL Rejuvenation Cocktail. It describes the rationale for combining Follistatin, Klotho and SIRT1 in a single rejuvenation strategy and the biological pathways through which the three interventions are intended to work together.
The paper has been submitted for publication to SEMAL and is available here as a KHL publication.
Under editorial consideration
Rejuvenation for the Living Generation
Rethinking Translational Medicine in an Era of Biological Plasticity
For decades, remarkable advances in biomedical science have been accompanied by a persistent problem: getting them to humans takes too long.
This policy analysis examines why promising interventions can remain trapped between scientific discovery and human application, why that delay matters especially to people already in later life, and how a different translational model can accelerate learning and application. It introduces Develop → Apply → Monitor → Adapt (DAMA) as a practical alternative.
Submitted to The Milbank Quarterly for peer-reviewed publication. The manuscript is currently under editorial consideration and is not being publicly distributed while the journal considers it.
research In preparation
Defining Longevity
What does it actually mean to achieve longevity?
This paper challenges the conventional use of life expectancy and survival alone as measures of longevity. It proposes a simple two-part definition: reach an advanced age and retain functional independence.
Under that definition, reaching 80 while remaining able to manage one’s own mobility, personal care and affairs means something fundamentally different from merely surviving to 80.
The paper develops this definition as a measurable concept with implications for medicine, public policy and the way societies judge progress in aging.